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pentobarbital will lessen the level or result of buprenorphine, prolonged-performing injection by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Modify Therapy/Watch Carefully. Clients who transfer to buprenorphine very long-acting injection from transmucosal buprenorphine coadministered with CYP3A4 inducers should be monitored to be certai